Expanding the utility of human induced pluripotent stem cell (hiPSC) forward programmed megakaryocytes: Creating a disease model of Thrombocytopenia with Absent Radii (TAR) syndrome and developmental stage appropriate cells
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Repository DOI
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Type
Thesis
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Authors
Abstract
[Restricted]
Description
Date
2022-08-01
Advisors
Ghevaert, Cedric
Keywords
CRISPR, forward programming, LYL1, megakaryocyte, platelet, pluripotent stem cell, RBM8A, RUNX3, thrombocytopenia absent radii (TAR) syndrome, transcription factor
Qualification
Doctor of Philosophy (PhD)
Awarding Institution
University of Cambridge
Rights
Sponsorship
Wellcome Trust (204017/Z/16/Z)
Wellcome Trust