Apollo - University of Cambridge Repository
This repository holds the research output of members of the University of Cambridge. It is delivered and managed by the University Library's Office of Scholarly Communication team.
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The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
(2019-11-05)Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds to and inhibits Drosha, a ... -
The role of selection and evolution in changing parturition date in a red deer population.
(2019-11-05)Changing environmental conditions cause changes in the distributions of phenotypic traits in natural populations. However, determining the mechanisms responsible for these changes-and, in particular, the relative contributions ... -
Comment: Why are females with Fabry disease affected?
(2019-10-22) -
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
(2019-11-04)CK2 is a constitutively active protein kinase overexpressed in numerous malignancies. Interaction between CK2α and CK2β subunits is essential for substrate selectivity. The CK2α/CK2β interface has been previously targeted ...
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