|Title: ||Sex chromosomes and genetic association studies|
|Authors: ||Clayton, David G|
|Issue Date: ||24-Nov-2009|
|Citation: ||Genome Medicine 2009, 1:110|
|Abstract: ||Abstract Although the literature concerning statistical testing for genotype-phenotype association in family-based and population-based studies is very extensive, until recently the sex chromosomes have received little attention. Here it is shown that the X chromosome in particular presents special problems with respect to efficient analysis of mixed-sex population studies, and as a result of X inactivation. This paper reviews recent developments in approaching these problems.|
|Description: ||RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.|
|Appears in Collections:||Scholarly works - Medical Genetics|
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