| Title: | Sex chromosomes and genetic association studies |
| Authors: | Clayton, David G |
| Issue Date: | 24-Nov-2009 |
| Citation: | Genome Medicine 2009, 1:110 |
| Abstract: | Abstract Although the literature concerning statistical testing for genotype-phenotype association in family-based and population-based studies is very extensive, until recently the sex chromosomes have received little attention. Here it is shown that the X chromosome in particular presents special problems with respect to efficient analysis of mixed-sex population studies, and as a result of X inactivation. This paper reviews recent developments in approaching these problems. |
| Description: | RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are. |
| URI: | http://www.dspace.cam.ac.uk/handle/1810/237625 http://dx.doi.org/10.1186/gm110 |
| Appears in Collections: | Scholarly works - Medical Genetics |
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